Étiquette : Immunology

BIOASTER

by jbertholdin Biotech, Pharma

BIOASTER

About the company

BIOASTER is the first Institute for Technological Innovation in Microbiology in France (Lyon and Paris, Pasteur Institute). They are Non-for-profit Technology Research Institute, active in the field of vaccine, immunomodulation, microbiota, anti-infectives, and IVD.
With BIOASTER, each project benefits from the right scientific and technology mix to address specific issues, quality in execution to meet high-standard requirements and case-by-case financial risk-sharing partnerships.
Their industrial partners come from a wide range of industries, including pharma, biotech, animal health, nutrition and diagnostics.

About the solution

Examples of partnership themes include for vaccine : Memory response /Longitudinal study, Efficacy, Memory response /Longitudinal study,correlate of protection, Breadth of protection, benchmarking with competitives vaccines, vaccine & adjuvant MOA, Exploratory research, preclinical & clinical biomarkers identification, system serology, immunometabolism (immunophenotyping at single cell), microbiota & immunity, host pathogen interaction.

Examples of partnership themes include for bioprocess- bioproduction & CMC: biomarkers identification for batch success/batch failure, digital tween & machine learning/deep Learning, method development & benchmarking, antigen characterization, potency assays development, Host Cell Proteins identification, CMC methods for in vitro mRNA production, mRNA formulation.

Website
Key information

– Therapeutic areas: Infectious & therapeutic vaccines, Immunology, Auto-immune diseases, Inflammatory diseases, Immuno-modulation, Microbiota, Antimicrobial, Antiviral, Ivd, Support to bioprocess optimization & bioproduction, Support to cmc

– Based in: Paris & Lyon (FRANCE)

– Employees: 51 – 200

– Created in: 2012

AP-HP PARIS

by jbertholdin Institutions, Service Providers & others

AP-HP (Greater Paris University Hospitals)

About the company

Assistance Publique – Hôpitaux de Paris is the leading university hospital center in Europe. With three missions, to care, to train, to research and to innovate, the AP-HP takes care of all the people who come to its hospitals, trains the professionals of today and tomorrow and is a major player in research.

About the solution

The AP-HP, through its status as a university hospital, has the mission to innovate. The search for new solutions to contribute to the well-being of patients, their loved ones and the professionals who support them is one of its primary missions. It supports and accompanies several forms of health innovation whoever it is.

Website
Key information

–  Therapeutic areas: Neurology, Cancerology, Immunology etc…

–  Based in: Paris (FRANCE)

–  Employees: 500+

–  Created in: 1900

ERBC GROUP

by jbertholdin Institutions, Service Providers & others

ERBC GROUP

About the company

ERBC group is a leader in discovery and non-clinical studies, offering to healthcare and chemical professionals a comprehensive range of discovery and preclinical models, regulatory pre-IND package and consultancy services to de-risk innovation and improve R&D productivity.

About the solution

At ERBC Group, THEY STRATEGIZE your approach to make your drug development a SUCCESS:
– Build on most relevant translational models
– Select best predictive biomarkers
– Choose state-of-the-art technologies.

Website
Key information

–  Therapeutic areas: Oncology – Cancer, Immunology, Inflammation, Neurology – Neurosciences, Cell and gene therapies, Cardiovascular, Infectious diseases, Metabolic diseases – Hepatology – Diabetes, Gastroenterology, Respiratory, Ophthalmology, Allergy, Dermatology, Orthopedics, Central nervous system, Nephrology, Cardiology, Pulmonology, Endocrinology, Hematology

–  Based in: Baugy, Toulouse, Lyon, Orleans (FRANCE)

–  Employees: 201-500

–  Created in: 2019

SURGE CARE

by jbertholdin Biotech, Pharma

SURGE CARE

About the company

Founded with the goal of revolutionizing precision medicine, Surge is an innovative company specializing in in-depth understanding of the immune system using AI. Thanks to significant technological advancements and a team of top-notch researchers coming from the US and from France, Surge is committed to creating innovative solutions to pave the way for personalized medicine of tomorrow. With the launch of its first product, PreCyte®, for predicting the risk of postoperative complications, and its premier laboratory, SurgeLab™, for acquiring individualized immune signatures, the company aims to become a leader in precision immune analysis.

About the solution

SurgeCare develops two main products :
– SurgeLab™, a lab platform focused on acquiring immune signatures, and
– PreCyte®, a range of medical devices for precision medicine.

Founded in 2021 with innovative technology for identifying predictive immune biomarkers, Surge, from 2021 to 2023, developed a first prototype to anticipate the risk of post-operative infections in patients undergoing major digestive surgery. A clinical study conducted from 2022 to 2023 revealed that their prototype outperforms existing methods by more than three times in terms of predictive capability. In 2024, this prototype enters its final phase of industrialization, with deployment planned as a pilot in the fourth quarter of 2024.

Meanwhile, in response to the growing interest of their partners, they have initiated the opening of their SurgeLab platform, which offers comprehensive immune screening, including ex-vivo blood stimulation, collection of biological parameters via a specialized panel, and data analysis through machine learning, reinforcing their commitment to innovation in precision medicine.

Website
Key information

–  Therapeutic areas: Surgery, Immunology, Precision Medicine

–  Based in: Strasbourg (FRANCE) & Stanford University (StartX) (USA)

–  Employees: 11 – 50

–  Created in: 2021

INOVARION

by jbertholdin Institutions, Service Providers & others

INOVARION

About the company

Inovarion is a Life Sciences company based in Paris offering preclinical and fundamental research services.

Since 2013, Inovarion provides support to the pharmaceutical, biotechnology industries and academics in the form of research services outsourced on a contract basis. They help biotech companies to reach clinical trials faster outsourcing their R&D to Inovarion in France.

They have been working as an extension of their partners’ teams for Sanofi, L’Oréal, Inserm (French NIH), Gustave Roussy, and many more.

About the solution

Inovarion has developed a strong expertise in bioinformatics, oncology, immunology and molecular biology.
They are well established in the research landscape in France and published +140 scientific papers in the highest ranked reviews (Nature, Science, The Lancet, Cell…).

Here are their main advantages:
⁃ Scientific French excellence
⁃ Cost effectiveness thanks to French tax credits : 25%-40% less vs US project cost
⁃ Talent loyalty & stability: less than 5% staff turnover per year in our team

Their goal is to build up close and long-term cooperation with pharmaceutical and biotechnologiy companies worldwide, to offer them in France, very attractive conditions, both financial and time-saving, for conducting top-notch fundamental and preclinical research and beyond that, to achieve together scientifical victories in medicine.

Website
Key information

–  Therapeutic areas: Immuno-oncology, Neuroscience, Dermatology, Oncology, Immunology

–  Based in: Paris (FRANCE)

–  Employees: 51-200

–  Created in: 2013

ARIANA PHARMACEUTICALS

by jbertholdin Digital Health

ARIANA PHARMACEUTICALS

About the company

Ariana Pharma is a leading Artificial Intelligence (AI) drug development company. Using its KEM® Artificial Intelligence (xAI) technology, Ariana helps its partners introduce personalized medicine clinical trial design into their protocols and optimize clinical endpoints, identify biomarkers of therapeutic response and potential synergistic therapies.

Ariana routinely collects and combines clinical data with omic data, immunological readouts (such as Fluorescence-Activated Cell Sorting (FACS)), microbiota, Patient Reported Outcomes (PRO) as well as Real World Evidence (RWE) data. Combining advanced data analytics, drug development, and regulatory expertise, Ariana helps translate findings into innovative clinical development plans and regulatory approvals.

With a growing number of successful therapeutic development programs, KEM® is an FDA-assessed technology that systematically explores combinations of biomarkers, producing more effective biomarker signatures for precision medicine. Founded in 2003 as a spin-off of the Institut Pasteur, Paris, France, the company operates a subsidiary in the United States since 2012.

About the solution

Ariana Pharma has developed an explainable artificial intelligence platform which explores all possible biomarker associations, generating results that can be used directly to design clinical trials and accelerate drug development. Based on the mathematical theories of Formal Concept Analysis and Gallois lattices, the power of the KEM® platform lies in its ability to deliver explainable results from small cohorts. KEM® is also effective at managing contradictions and heterogeneous data, ensuring the identification of relevant and accurate hypotheses that meet the needs of precision medicine.

Website
Key information

–  Therapeutic areas: Oncology, CNS, Cardiometabolic, Immunology

–  Based in: Paris (FRANCE)

–  Employees: 11-50

–  Created in: 2003

CLINSEARCH

by jbertholdin Institutions, Service Providers & others

CLINSEARCH

About the company

ClinSearch is a full service European CRO, established in 1999, offering clinical research and medical evaluation services throughout Europe, as well as the Middle East and the United States.

They have conducted hundreds of studies, from phase I to IV studies, early access programs, post-marketing studies, RWE, PASS, PAES, database analyses and medico-economic studies, involving 1 patient up to 220,000 subjects.
Their customers include global and local medical device, biotechnology and pharmaceutical companies, as well as public health institutions.

About the solution

Full service offering from A to Z: methodological input to study design through to peer-reviewed publications, passing via in-house development of sophisticated healthcare tools (EDC, ePRO, …).

The in-house team of over 70 people work from our headquarters in Malakoff (France), but hail from ~15 different countries and speak over 10 languages, and are trained to a high standard (MD, PhD, PharmD, MS, MPH …).

Website
Key information

–  Therapeutic areas: Addiction, Aesthetics, Algorithm, Software, Cardiovascular, Dermatology, Fertility, Immunology, Infectiology, Hematology, Neurology, Neuromuscular, Neurovascular, Nursing care, Orthopedic, Oncology, Rheumatology, Rare diseases, Respiratory, Surgery, Urology

–  Based in: Boston (USA)

–  Employees: 51-200

–  Created in: 1999

SATT AxLR

by jbertholdin Institutions, Service Providers & others

SATT AxLR

About the company

SATT AxLR is a TTO based in south of France with a focus on innovative health projects from academic teams. SATT AxLR is funding early stages to allow project reaching a stage for technical transfer or company creation.

About the solution

SATT AxLR provide advice, contacts, funding to academic researchers (Universities, Hospitals, Public Instittutes,..) and generate intellectual property that is available for licensing.

Website
Key information

–  Therapeutic areas: Oncology, Immunology, CNS, Cardiology, Rare diseases, Obesity, Cell therapy, Medical Device

–  Based in: Montpellier (FRANCE)

–  Employees: 11 – 50

–  Created in: 2012

FIRALIS MOLECULAR PRECISION

by jbertholdin Biotech, Pharma

FIRALIS MOLECULAR PRECISION

About the company

Firalis Molecular Precision (FMP), established in 2019 and rooted in the Firalis Group, operates as a leading Contract Research Organization (CRO) from Huningue, France.

Specialized in biomarker discovery and multi-omic analysis (genomics, proteomics, metabolomics), FMP accelerates precision medicine by improving diagnostics, understanding disease mechanisms, and evaluating drug efficacy. With advanced laboratories and a dedicated team of over 55 experts, FMP supports biotech and pharma companies globally, offering a suite of services that span pre-clinical to clinical trials, thus playing a pivotal role in advancing healthcare innovations.

About the solution

Firalis Molecular Precision (FMP) is at the forefront of the multi-omics revolution bringing progress and innovation to the biopharmaceutical industry. By harnessing advanced -omics technologies and bioinformatics, they excel in identifying promising therapeutic targets and enhancing the drug development process for greater speed and reliability. Their state-of-the-art multi-omics solutions facilitate precise, high-throughput genomics, transcriptomics, and proteomics, leading to pioneering healthcare breakthroughs.

Website
Key information

–  Therapeutic areas: Neurology, Oncology, Immunology  

–  Based in: Huningue (FRANCE) & Cambridge (USA)

–  Employees: 51 – 200

–  Created in: 2016

QIMA LIFE SCIENCES

by jbertholdin Institutions, Service Providers & others

QIMA LIFE SCIENCES

About the company

QIMA Life Sciences brings together QIMA Bioalternatives, Newtone Technologies, and Monasterium Laboratory. The companies provide innovative testing and research solutions ranging from in silico screening to clinical imaging, as well as in vitro and ex vivo assays and non-invasive clinical sample bioanalysis. They also offer the exclusive “Blood assay solutions” for fresh whole blood testing.

They contribute to the development of testing methods as an alternative to animal experimentation, by offering solutions dedicated to preclinical research and to the development of drug candidates and to cosmetic active ingredients and formulations.

About the solution

The company provides a 360° offer with innovative testing and research solutions ranging from in silico screening to clinical imaging, as well as in vitro and ex vivo assays and non-invasive clinical sample bioanalysis.

Website
Key information

–  Therapeutic areas: Dermatology, Oncology, immunology, Neurobiology

–  Based in: Gençay (FRANCE)

–  Employees: 51 – 200

– Created in: 1996